Universal solid tumor therapy with CD5-deleted, DSG2-directed CAR-T cells. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

Cancer immunotherapy has been transformed by engineered T cells, but those bespoke treatments are slow, expensive, and out of reach for many patients who need help quickly. A new way to generate vast ...

Invariant natural killer T (iNKT) cells represent a distinctive subset of lymphocytes that bridge the innate and adaptive immune systems. Characterised by a semi‐invariant T cell receptor (TCR) and ...

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping ...

As the trained killers of the immune system, cytotoxic T cells silently save our lives every day—vanquishing viruses before they can run amok, and putting nascent cancer cells out of business before ...

Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million ...

Powerful white blood cells referred to as CD8 killer T cells enable the body to control infections and fight cancer. But when ...